News

Why pancreatic ductal adenocarcinoma is so lethal

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire a deadly new identity, and recruit nearby cells to help them grow, promote inflammation, and invade nearby tissues. This understanding could lead to new … Continued

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Microbe Mappers Are Tracking Covid-19’s Invisible Traces

DURING THE SECOND week of March, as the World Health Organization declared Covid-19 a global pandemic, a team of latex-gloved scientists from Cornell Weill Medical School fanned out across Penn Station armed with packs of sterile, long-armed swabs and a tripod-mounted instrument for capturing air samples. In New York City, the 100th person had just tested positive … Continued

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‘Spider-Man’ Immune Response May Promote Severe COVID-19

A menagerie of immune cells and proteins defend the human body, and a relatively obscure member of this crew is getting new attention as a possible target for treating COVID-19. Neutrophils make up more than half of our white blood cells and are often the first to arrive at the scene of infection. But historically … Continued

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What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

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How pancreatic RAS tumors protect themselves. Researchers point to a new protein — and maybe a new treatment

A couple years back, some cardiovascular specialists at Boston’s Brigham and Women’s Hospital stumbled across a surprising result. Novartis had tasked them with carrying out the long-range Phase III trial for canakinumab, an experimental anti-inflammatory drug the company was trying to market for cardiovascular disease. The main results were mixed — modest reductions in fatal … Continued

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