News

Exploration of Pregnancy-Related Changes in Breast Tissue

ONCOLOGY TIMES – A century-old medical understanding recognizes the fact that a full-term pregnancy early in a woman’s life dramatically decreases her risk of breast cancer. Camila dos Santos, PhD, Assistant Professor at the Cancer Center of Cold Spring Harbor Laboratory, wants to know more about that phenomenon. She has set about interrogating breast tissue—both … Continued

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The Tisch Cancer Institute and Precision Immunology Institute at Mount Sinai Launch Center for Computational Immunology

Newswise — (New York, NY – May 9, 2019) — The Tisch Cancer Institute and the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai have launched the Center for Computational Immunology, a hub that will help researchers studying cancer, genomics, machine learning, and immunology collaborate to find better targeted immunotherapies for patients. Benjamin … Continued

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President Bruce Stillman wins prestigious Gairdner Award

Cold Spring Harbor, NY — Dr. Bruce Stillman, President and CEO of Cold Spring Harbor Laboratory (CSHL), has been awarded the 2019 Canada Gairdner International Award in honor of his pivotal contributions to basic research. The Canada Gairdner International Award recognizes researchers who have made seminal discoveries or contributions to biomedical science. Dr. Stillman is being honored for “pioneering … Continued

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Study identifies link between DNA-protein binding, cancer onset

Researchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes. The research focuses on chromatin, the DNA-protein complex where all genes reside. Specifically, it evaluates chromatin’s … Continued

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New mRNA Cancer Drivers Revealed in Chronic Lymphocytic Leukemia

NEW YORK (GenomeWeb) – New evidence has emerged today showing that the inactivation or alteration of cancer suppressor genes can take place even if DNA itself remains unaltered. Reporting in Nature, investigators demonstrated that changes in mRNA due to a process called intronic polyadenylation (IPA) can drive development of some cancers by altering gene expression in … Continued

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Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports. The researchers discovered a way to grow the immune cells, called dendritic cells, at large scale in the lab to study them … Continued

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‘Hijacked’ cell response to stress reveals promising drug targets for blood cancer

A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows. The discovery that the NOTCH1 pathway takes control of heat shock transcription factor 1 (HSF1) signaling in T cell acute lymphoblastic leukemia, or … Continued

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CSHL’s Camila dos Santos scores family’s second $600K award

TBR News Media They aren’t quite wonder twins, but some day the dedicated work of husband and wife scientists Christopher Vakoc and Camila dos Santos may help people batting against a range of cancers, from leukemia to breast cancer. Dos Santos and Vakoc are the first family of prize winners in the Pershing Square Foundation’s … Continued

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Researchers discover new type of lung cancer

Cold Spring Harbor, NY — Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease. “Cancer is not one thing, it’s actually hundreds of distinct diseases.” This common refrain helps explain the frustrating experience oncologists have … Continued

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SBU’s Benjamin Martin scores first Sohn Research Prize

TBR News Media Up and coming scientists are often stuck in the same position as promising professionals in other fields. To get the funding for research they’d like to do, they need to show results, but to get results, they need funding. Joseph Heller, author of “Catch 22,” would certainly relate. A New York-based philanthropy … Continued

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