NEW YORK (GenomeWeb) – New evidence has emerged today showing that the inactivation or alteration of cancer suppressor genes can take place even if DNA itself remains unaltered. Reporting in Nature, investigators demonstrated that changes in mRNA due to a process called intronic polyadenylation (IPA) can drive development of some cancers by altering gene expression in … Continued
TBR News Media They aren’t quite wonder twins, but some day the dedicated work of husband and wife scientists Christopher Vakoc and Camila dos Santos may help people batting against a range of cancers, from leukemia to breast cancer. Dos Santos and Vakoc are the first family of prize winners in the Pershing Square Foundation’s … Continued
Cold Spring Harbor, NY — Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease. “Cancer is not one thing, it’s actually hundreds of distinct diseases.” This common refrain helps explain the frustrating experience oncologists have … Continued
TBR News Media Up and coming scientists are often stuck in the same position as promising professionals in other fields. To get the funding for research they’d like to do, they need to show results, but to get results, they need funding. Joseph Heller, author of “Catch 22,” would certainly relate. A New York-based philanthropy … Continued
Cold Spring Harbor, NY – Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that cells lacking the tumor-suppressor protein PTEN–a feature of many cancers– are particularly vulnerable to drugs that impair their energy-producing mitochondria. Such drugs induce them to literally eat themselves to death, the research shows. Unlike normal cells, cells without PTEN seem … Continued
Researchers at the Sloan Kettering Institute and the Weill Cornell Graduate School of Medical Sciences in New York have developed a machine learning approach to design personalized nanoparticle therapies for cancer. Personalized cancer therapies aim to provide a treatment that is tailored to the genetic makeup of a patient’s tumor. They can still cause side effects, however, when they … Continued
PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Now Accepting Applications for the 2018 Prize for Early-Career Cancer Scientists
NEW YORK, Oct. 2, 2017 /PRNewswire-USNewswire/ — The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for its 2018 Prize for Young Investigators in Cancer Research. The prize of $200,000 per year for up to three years is awarded annually to at least six New York City-based scientists, enabling them to … Continued
We report frequently enough about research grants and prizes specifically for young investigators—particularly in the biomedical sciences—that some readers have asked why so many foundations make it a point to earmark this early-career funding. What's the obsession with youth? We gray-hairs want to know.
By Olivia Tournay Flatto (Disease Models & Mechanisms) – Summary: Philanthropists and scientists share many common interests, and yet they are not familiar with each other’s ways of thinking. This Editorial highlights how to improve their mutual understanding to advance research and life sciences.