Few cancer treatments are generating more excitement these days than immunotherapy—drugs based on the principle that the immune system can be harnessed to detect and kill cancer cells, much in the same way that it goes after infectious microorganisms. Yet these treatments only benefit some patients, and remain ineffective in the vast majority of cases. … Continued
PUBLIC RELEASE: 8-JAN-2018 Cold Spring Harbor, NY – Cancer researchers today announced they have developed a way of sidelining one of the most dangerous “bad actors” in leukemia. Their approach depends on throwing a molecular wrench into the gears of an important machine that sets genes into motion, enabling cancer cells to proliferate. In tests in … Continued
October 9, 2017—BRONX, NY—Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells. The new treatment approach, described in today’s issue of Cancer Cell, was directed against acute myeloid leukemia (AML) cells but may also have potential for attacking other types of cancers. “We’re hopeful … Continued
After 18 months being incubated by Versant Ventures, upstart Repare Therapeutics has emerged from stealth mode with an impressive $68 million, backing from Celgene and some big-name execs. The Montreal and Cambridge, Massachusetts, biotech saw founding investor Versant Ventures co-lead the series A round with MPM Capital. They were also joined by other syndicate investors … Continued
Researchers from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have received two grants from the Sohn Conference Foundation to advance their investigation into how cancer spreads in children. Dr. David Lyden, the Stavros S. Niarchos Professor in Pediatric Cardiology and a professor of pediatrics, Dr. Haiying Zhang, an assistant professor of cell and … Continued
Some people struggle to find their paths in life. Not Chris Mason, PhD, Associate Professor and geneticist at Weill Cornell Medicine in New York City. He had already determined he wanted to be a geneticist by the time he reached eighth grade. “I was—and still am—a curious kid. I wanted to know how the world … Continued
Ali Brivanlou slides open a glass door at the Rockefeller University in New York to show off his latest experiments probing the mysteries of the human embryo. “As you can see, all my lab is glass — just to make sure there is nothing that happens in some dark rooms that gives people some weird … Continued
Abstract: Before completing a PhD in immunology at the Humbolt University of Berlin, Christine Mayr received a medical degree from the Freie Universität Berlin. She received postdoctoral training with Michael Hallek at the Ludwig Maximillian University in Munich.
Findings By Weill Cornell Medicine Explain Paget’s “Seed and Soil” Theory of Metastasis
Abstract: Cohesin complex members have recently been identified as putative tumor suppressors in hematologic and epithelial malignancies. The cohesin complex guides chromosome segregation; however, cohesin mutant leukemias do not show genomic instability.