News

PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2023 Prize for Radically Innovative, Early-Career Cancer Researchers

October 3rd, 2022

The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2023 Prize for Radically Innovative, Early-Career Cancer Researchers NEW YORK, OCTOBER 3, 2022 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for the 2023 Pershing Square Sohn Prize for Young Investigators in Cancer … Continued

Colorectal cancer tumors both helped and hindered by T cells

July 25th, 2022 / EUREKALERT / THE ROCKEFELLER UNIVERSITY

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated. While some studies have shown that white blood cells heroically restrict tumor growth and combat colorectal cancer, equally compelling evidence casts the white blood cells as malignant co-conspirators—bolstering the tumor and helping it spread. Now, … Continued

PRESS RELEASE: THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $4.2M TO SEVEN EMERGING TRAILBLAZERS IN CANCER RESEARCH

June 7th, 2022 / The Pershing Square Sohn Cancer Research Alliance

THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $4.2M TO SEVEN EMERGING TRAILBLAZERS IN CANCER RESEARCH The Pershing Square Sohn Prize Has Committed More Than $35 Million to 59 Scientists in the Greater New York Area to Support Bold Cancer Research NEW YORK, JUNE 7, 2022 (Business Wire) – The Pershing Square Sohn Cancer Research … Continued

Scientists Discover Gene Mutation That Signals Aggressive Melanoma

April 7th, 2022 / MOUNT SINAI HEALTH SYSTEM

Newswise — New York, NY (April 6, 2022)— Mutation of a gene called ARID2 plays a role in increasing the chance that melanoma, a deadly skin cancer, will turn dangerously metastatic, Mount Sinai researchers report. The findings suggest that patients whose melanoma tumors have an ARID2 mutation may have a more aggressive cancer and may need to be treated … Continued

HIV drug shows promise against metastatic cancer

April 5th, 2022 / Alice McCarthy, THE HARVARD GAZETTE

A drug widely used in HIV therapy has shown to stop disease progression in 25 percent of patients with fourth-line metastatic colorectal cancer. Findings from the trial, published in Cancer Discovery, raise the possibility of an unexpected promising direction in cancer treatment, not just colorectal cancer. The drug used in the study was lamivudine, a reverse transcriptase inhibitor. … Continued

Hands, Feet, and Fins: The Connection That Explains Acral Melanoma

March 31st, 2022 / MEMORIAL SLOAN KETTERING

To understand cancer in humans, researchers at the Sloan Kettering Institute (SKI) are turning to our distant relatives from 425 million years ago: fish. A lot has evolved since then: Fish use their fins to swim, whereas we use our hands to play Wordle. But there remains a deep similarity, explains 2017 Pershing Square Sohn Prize winner Richard … Continued

SKI Scientists Discover a New Twist on an 80-Year-Old Biochemical Pathway

March 17th, 2022 / MEMORIAL SLOAN KETTERING

Every year, thousands of biochemistry majors and medical students around the world learn to memorize the major biochemical pathways that allow cells to function. How these 10 or so pathways are described in textbooks hasn’t changed much since the early 20th century, when they were first discovered. But with the resurgence of interest in cancer metabolism in … Continued

Old Drug May Have New Trick: Protecting Against COVID-19 Lung Injury

February 9th, 2022 / WEILL CORNELL MEDICINE

An FDA-approved drug that has been in clinical use for more than 70 years may protect against lung injury and the risk of blood clots in severe COVID-19 and other disorders that cause immune-mediated damage to the lungs, according to a preclinical study from researchers at Weill Cornell Medicine and Cold Spring Harbor Laboratory. The … Continued

PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2022 Prize for Early-Career, Radically Innovative Cancer Researchers

October 4th, 2021 / The Pershing Square Sohn Cancer Research Alliance

The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2022 Prize for Early-Career, Radically Innovative Cancer Researchers NEW YORK, OCTOBER 4, 2021 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for the 2022 Pershing Square Sohn Prize for Young Investigators in Cancer … Continued

Why Are Only Some Cells ‘Competent’ to Form Cancer? MSK Scientists Say Context Is Key

September 3rd, 2021 / MEMORIAL SLOAN KETTERING

Right now, in your body, lurk thousands of cells with DNA mistakes that could cause cancer. Yet only in rare instances do these DNA mistakes, called genetic mutations, lead to a full-blown cancer. Why? The standard explanation is that it takes a certain number of genetic “hits” to a cell’s DNA to push a cell … Continued