Pershing Square Sohn Cancer Research Alliance


The Pershing Square Sohn Cancer Research Alliance is dedicated to playing a catalytic role in accelerating cures for cancer by enabling the pursuit of the most innovative and advanced cancer research and by facilitating collaborations between science and business.

Early-Stage Funding for Cancer Research

The Prize for young investigators provides early-stage funding opportunities to New York scientists with innovative ideas in cancer research. The program surrounding the Prize is a catalyst in bridging the gap between the academic scientific community and the business community.

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2018 Prize Winners

News

August 27, 2018
NEW MRNA CANCER DRIVERS REVEALED IN CHRONIC LYMPHOCYTIC LEUKEMIA

NEW YORK (GenomeWeb) – New evidence has emerged today showing that the inactivation or alteration of cancer suppressor genes can take place even if DNA itself remains unaltered. Reporting in Nature, investigators demonstrated that changes in mRNA due to a process called intronic polyadenylation (IPA) can drive development of some cancers by altering gene expression in a way that interferes with the proper functioning of tumor suppression mechanisms. Led by Memorial Sloan Kettering Cancer Center molecular biologist Christine Mayr, the study involved sequencing normal and cancerous cells from a small cohort of patients with chronic lymphocytic leukemia, which revealed that IPA-driven mRNA changes do take place, and that — at least in this cancer type — can occur much more frequently than corresponding mutations in DNA.

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Events

May 23, 2018 
5TH ANNUAL PERSHING SQUARE SOHN PRIZE DINNER

On Wednesday, May 23rd, the Pershing Square Research Alliance held its Fifth Annual Prize Dinner at the Park Avenue Armory, awarding its 2018 Pershing Square Sohn Prize for Young Investigators in Cancer Research to seven exceptional groundbreaking scientists in New York City. The evening began with a panel discussion on synthetic biology, featuring Dr. Jef Boeke, Director of the Institute for Systems Genetics at NYU School of Medicine and Dr. Floyd Romesberg, Professor in the Department of Chemistry at The Scripps Research Institute. Ira Flatow, Host and Executive Producer of the popular podcast Science Friday, moderated the discussion.

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“The Pershing Square Foundation is proud to support scientific leaders in the fight against cancer.”

Bill Ackman, Co-Founder. The Pershing Square Foundation