Pershing Square Sohn Cancer Research Alliance


The Pershing Square Sohn Cancer Research Alliance is dedicated to playing a catalytic role in accelerating cures for cancer by enabling the pursuit of the most innovative and advanced cancer research and by facilitating collaborations between science and business.

Early-Stage Funding for Cancer Research

The Prize for young investigators provides early-stage funding opportunities to New York scientists with innovative ideas in cancer research. The program surrounding the Prize is a catalyst in bridging the gap between the academic scientific community and the business community.

LEARN MORE2019 PRIZE WINNERS

2019 Prize Winners

News

November 4, 2019
SCIENTISTS IDENTIFY PROTEIN THAT PROMOTES BRAIN METASTASIS

WEILL CORNELL MEDICINE – A protein that breast, lung and other cancers use to promote their spread—or metastasis—to the brain, has been identified by a team led by Weill Cornell Medicine and New York-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain metastases, which are a frequent cause of cancer deaths.

In their study, published Nov. 4 in Nature Cell Biology, the scientists found that CEMIP prompts blood vessel and resident immune cells in the brain to produce inflammatory molecules, which in turn support the survival and progression of cancer cells to form brain tumors. In lab-dish and animal-model experiments, removing CEMIP greatly impeded this brain metastasis process. In tests on human patients’ breast and lung tumors, the researchers linked high CEMIP levels to a high risk of metastasis to the brain.

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Events

October 22, 2019 
THIRD ANNUAL PERSHING SQUARE SOHN RETREAT

On Tuesday, October 22nd, 2019, the Pershing Square Sohn Cancer Research Alliance held its Third Annual Pershing Square Sohn Retreat in Nicholls-Biondi Hall at Cold Spring Harbor Laboratory in Long Island.

The Retreat highlighted the 2016 Pershing Square Sohn Prize winners who had just finished their third and final year of funding. These innovative scientists presented their research done over the past three years to their peers and mentors, with robust Q&A discussions regarding their data, next steps, and potential collaborations. The day concluded with a keynote by Scientific Review Council member David C. Lyden, MD, PhD, the Stavros S. Niarchos Professor in the Departments of Pediatrics and Developmental Biology at Weill Cornell Medicine, on understanding the role of tumor-secreted exosomes in cancer metastasis.

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“The Pershing Square Foundation is proud to support scientific leaders in the fight against cancer.”

Bill Ackman, Co-Founder. The Pershing Square Foundation