News

Why Are Only Some Cells ‘Competent’ to Form Cancer? MSK Scientists Say Context Is Key

Right now, in your body, lurk thousands of cells with DNA mistakes that could cause cancer. Yet only in rare instances do these DNA mistakes, called genetic mutations, lead to a full-blown cancer. Why? The standard explanation is that it takes a certain number of genetic “hits” to a cell’s DNA to push a cell … Continued

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Can mRNA Vaccines Fight Pancreatic Cancer? MSK Clinical Researchers Are Trying to Find Out

Messenger RNA (mRNA) vaccines may be the hottest thing in science now as they help turn the tide against COVID-19. But even before the pandemic began, Memorial Sloan Kettering researchers had already been working to use mRNA vaccine technology to treat cancer. Vinod Balachandran a physician-scientist affiliated with the David M. Rubenstein Center for Pancreatic Cancer Research and … Continued

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How pancreatic cancer cells dodge drug treatments

Cancer cells can become resistant to treatments through adaptation, making them notoriously tricky to defeat and highly lethal. Cold Spring Harbor Laboratory (CSHL) Cancer Center Director and Pershing Square Sohn Cancer Research Alliance Scientific Review Council member David Tuveson and his team investigated the basis of “adaptive resistance” common to pancreatic cancer. They discovered one of the backups … Continued

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When cancer cells “put all their eggs in one basket”

Normal cells usually have multiple solutions for fixing problems. For example, when DNA becomes damaged, healthy white blood cells can use several different strategies to make repairs. But cancer cells may “put all their eggs in one basket,” getting rid of all backup plans and depending on just one pathway to mend their DNA. Cold … Continued

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PRESS RELEASE: THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $3.6 MILLION TO SIX EMERGING PIONEERS IN CANCER RESEARCH

THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $3.6 MILLION TO SIX EMERGING PIONEERS IN CANCER RESEARCH  The Pershing Square Sohn Prize Has Committed More Than $30 Million to 52 Scientists in the New York Area to Support Bold Cancer Research NEW YORK, MAY 18, 2021 (Business Wire) – The Pershing Square Sohn Cancer Research … Continued

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Cancer Researchers Discover What’s Driving “Brain Fog” in People With COVID-19

A unique collaboration among experts from several areas within MSK leads to findings about how inflammation appears to be driving the neurologic effects seen in some COVID-19 patients. One of the dozens of unusual symptoms that have emerged in COVID-19 patients is a condition that’s informally called “COVID brain” or “brain fog.” It’s characterized by confusion, headaches, … Continued

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PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2021 Prize for Early-Career, Radically Innovative Cancer Researchers

The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2021 Prize for Early-Career, Radically Innovative Cancer Researchers NEW YORK, OCTOBER 5, 2020 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for its 2021 Prize for Young Investigators in Cancer Research. The prize … Continued

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Tiny Protein Packages Released from Cells May Serve as Biomarkers for Early Blood-Based Cancer Diagnosis

Tiny packets called extracellular vesicles and particles (EVPs), released by cancer and immune cells, contain specific proteins that may serve as reliable biomarkers for diagnosing early-stage cancer, according to investigators at Weill Cornell Medicine and Memorial Sloan Kettering. A new study published August 13 in Cell identifies new biomarkers in EVPs that can be used to help discriminate these … Continued

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PRESS RELEASE: THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $4.2M TO SEVEN RISING LEADERS IN CANCER RESEARCH

THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $4.2M TO SEVEN RISING LEADERS IN CANCER RESEARCH The Pershing Square Sohn Prize Has Supported 46 Cancer Scientists in the New York Life Science Ecosystem by Funding High-Risk, High-Reward Research NEW YORK, JULY 29, 2020 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance today announced … Continued

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The first mouse model of human pancreas cancer subtypes

Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help researchers investigate why some pancreatic cancers are more aggressive than others and what causes them to progress, paving the way to … Continued

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