COLUMBIA UNIVERSITY IRVING MEDICAL CENTER/EUREKALERT – Columbia University will award the 2019 Louisa Gross Horwitz Prize to three scientists: Lewis C. Cantley, Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center, New York, NY, USA, David M. Sabatini, Massachusetts Institute of Technology, Cambridge, Massachusetts, and Howard Hughes Medical Institute, Chevy Chase, MD, USA, and Peter K. … Continued
ONCOLOGY TIMES – A century-old medical understanding recognizes the fact that a full-term pregnancy early in a woman’s life dramatically decreases her risk of breast cancer. Camila dos Santos, PhD, Assistant Professor at the Cancer Center of Cold Spring Harbor Laboratory, wants to know more about that phenomenon. She has set about interrogating breast tissue—both … Continued
MIRAGE NEWS – A molecular pathway known for responding to cellular stress also produces pain-inducing molecules in immune cells in mice, according to a new study by scientists at Dana-Farber Cancer Institute, Weill Cornell Medicine and Wake Forest University School of Medicine. The investigators found that blocking this pathway can reduce pain. The findings, published online in the … Continued
Newswise — (New York, NY – May 9, 2019) — The Tisch Cancer Institute and the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai have launched the Center for Computational Immunology, a hub that will help researchers studying cancer, genomics, machine learning, and immunology collaborate to find better targeted immunotherapies for patients. Benjamin … Continued
Cold Spring Harbor, NY — Dr. Bruce Stillman, President and CEO of Cold Spring Harbor Laboratory (CSHL), has been awarded the 2019 Canada Gairdner International Award in honor of his pivotal contributions to basic research. The Canada Gairdner International Award recognizes researchers who have made seminal discoveries or contributions to biomedical science. Dr. Stillman is being honored for “pioneering … Continued
Researchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes. The research focuses on chromatin, the DNA-protein complex where all genes reside. Specifically, it evaluates chromatin’s … Continued
NEW YORK (GenomeWeb) – New evidence has emerged today showing that the inactivation or alteration of cancer suppressor genes can take place even if DNA itself remains unaltered. Reporting in Nature, investigators demonstrated that changes in mRNA due to a process called intronic polyadenylation (IPA) can drive development of some cancers by altering gene expression in … Continued
For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports. The researchers discovered a way to grow the immune cells, called dendritic cells, at large scale in the lab to study them … Continued
A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows. The discovery that the NOTCH1 pathway takes control of heat shock transcription factor 1 (HSF1) signaling in T cell acute lymphoblastic leukemia, or … Continued
Cold Spring Harbor, NY — Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease. “Cancer is not one thing, it’s actually hundreds of distinct diseases.” This common refrain helps explain the frustrating experience oncologists have … Continued