News

Can mRNA Vaccines Fight Pancreatic Cancer? MSK Clinical Researchers Are Trying to Find Out

Messenger RNA (mRNA) vaccines may be the hottest thing in science now as they help turn the tide against COVID-19. But even before the pandemic began, Memorial Sloan Kettering researchers had already been working to use mRNA vaccine technology to treat cancer. Vinod Balachandran a physician-scientist affiliated with the David M. Rubenstein Center for Pancreatic Cancer Research and … Continued

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How pancreatic cancer cells dodge drug treatments

Cancer cells can become resistant to treatments through adaptation, making them notoriously tricky to defeat and highly lethal. Cold Spring Harbor Laboratory (CSHL) Cancer Center Director and Pershing Square Sohn Cancer Research Alliance Scientific Review Council member David Tuveson and his team investigated the basis of “adaptive resistance” common to pancreatic cancer. They discovered one of the backups … Continued

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When cancer cells “put all their eggs in one basket”

Normal cells usually have multiple solutions for fixing problems. For example, when DNA becomes damaged, healthy white blood cells can use several different strategies to make repairs. But cancer cells may “put all their eggs in one basket,” getting rid of all backup plans and depending on just one pathway to mend their DNA. Cold … Continued

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Cancer Researchers Discover What’s Driving “Brain Fog” in People With COVID-19

A unique collaboration among experts from several areas within MSK leads to findings about how inflammation appears to be driving the neurologic effects seen in some COVID-19 patients. One of the dozens of unusual symptoms that have emerged in COVID-19 patients is a condition that’s informally called “COVID brain” or “brain fog.” It’s characterized by confusion, headaches, … Continued

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Tiny Protein Packages Released from Cells May Serve as Biomarkers for Early Blood-Based Cancer Diagnosis

Tiny packets called extracellular vesicles and particles (EVPs), released by cancer and immune cells, contain specific proteins that may serve as reliable biomarkers for diagnosing early-stage cancer, according to investigators at Weill Cornell Medicine and Memorial Sloan Kettering. A new study published August 13 in Cell identifies new biomarkers in EVPs that can be used to help discriminate these … Continued

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PRESS RELEASE: THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $4.2M TO SEVEN RISING LEADERS IN CANCER RESEARCH

THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE AWARDS $4.2M TO SEVEN RISING LEADERS IN CANCER RESEARCH The Pershing Square Sohn Prize Has Supported 46 Cancer Scientists in the New York Life Science Ecosystem by Funding High-Risk, High-Reward Research NEW YORK, JULY 29, 2020 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance today announced … Continued

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The first mouse model of human pancreas cancer subtypes

Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help researchers investigate why some pancreatic cancers are more aggressive than others and what causes them to progress, paving the way to … Continued

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A Wisconsin City Experiments With a Faster, DIY Covid-19 Test

In a former boxing gym in Racine, firefighters are trying out a spit test that’s simpler and cheaper than PCR. Could it change how we screen for the virus? EACH MORNING AT 7, Brian Wolf, the fire chief of Racine, Wisconsin, arrives for work in a neglected corner of a building called the City Hall … Continued

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PRESS RELEASE: THE PERSHING SQUARE FOUNDATION AWARDS $3 MILLION TO INNOVATIVE SARS-COV-2 RESEARCH PROJECTS

THE PERSHING SQUARE FOUNDATION AWARDS $3 MILLION TO INNOVATIVE SARS-COV-2 RESEARCH PROJECTS Foundation Supports Leaders in Life Science who have Refocused Work to Combat the Coronavirus Pandemic NEW YORK, July 7, 2020 (Businesswire) – The Pershing Square Foundation (the “Foundation”) today announced that it has awarded $3 million to nineteen recipients at ten academic research institutions … Continued

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Why pancreatic ductal adenocarcinoma is so lethal

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire a deadly new identity, and recruit nearby cells to help them grow, promote inflammation, and invade nearby tissues. This understanding could lead to new … Continued

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