News

Pancreatic cancer hijacks a brain-building protein

CSHL (February 14, 2024) — Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research—eight years in the making. It could help slow the disease’s deadly spread. In 2017, as a postdoc in CSHL’s Tuveson lab, Chang-il Hwang and collaborators from the Vakoc lab uncovered … Continued

Read More

PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2024 Prize for Rising Leaders in Cancer Research

THE PERSHING SQUARE SOHN CANCER RESEARCH ALLIANCE IS NOW ACCEPTING APPLICATIONS FOR ITS 2024 PRIZE FOR RISING LEADERS IN CANCER RESEARCH NEW YORK, SEPTEMBER 25, 2023 (The Pershing Square Foundation, Business Wire) — The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for the 2024 Pershing Square Sohn Prize for … Continued

Read More

Cancer Breakthrough: Yale Scientists Discover New Way To Reduce Friendly Fire in Cell Therapy

SciTech Daily –New York, NY (July 31, 2023) — New recent research from Yale has discovered a method to control the self-destructive tendencies of certain killer T cells utilized in cancer therapy. CAR T-cell (chimeric antigen receptor) therapy, a promising form of immunotherapy, involves reprogramming the patient’s T cells to enhance their ability to identify … Continued

Read More

Lab-grown mini lungs could accelerate the study of respiratory diseases

The Rockefeller University – When we’re driving to a new destination, we often turn down the stereo as we follow the directions. What had been music suddenly sounds like noise, and it interferes with our focus. Our understanding of how infectious diseases like COVID affect human lungs has been similarly confounded by noise. Data from … Continued

Read More

Breaking New Ground With Blood Cancers Through the Lens of Splicing Factor Mutations

Icahn School of Medicine at Mt. Sinai – Recent work with induced pluripotent stem cells has helped uncover complex mechanisms in myelodysplastic syndrome and acute myeloid leukemia for the first time. This discovery could pave the way for improving current treatments, or even for finding new ones. A decade ago, somatic mutations—those that occur after … Continued

Read More

Yale scientist’s ‘powerful,’ new gene editing technique promises to speed research

CT Insider — New Haven, CT (February 21, 2023) A new gene editing technique developed by scientists from Yale University offers a powerful new tool to interrogate how genes work across a swath of biological disciplines, from cancer research to immunology.  According to a study published in Nature Biotechnology, the technique called “CLASH” allows potentially thousands … Continued

Read More

PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2023 Prize for Radically Innovative, Early-Career Cancer Researchers

The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2023 Prize for Radically Innovative, Early-Career Cancer Researchers  NEW YORK, OCTOBER 3, 2022 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for the 2023 Pershing Square Sohn Prize for Young Investigators in Cancer … Continued

Read More

Colorectal cancer tumors both helped and hindered by T cells

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated. While some studies have shown that white blood cells heroically restrict tumor growth and combat colorectal cancer, equally compelling evidence casts the white blood cells as malignant co-conspirators—bolstering the tumor and helping it spread. Now, … Continued

Read More

Scientists Discover Gene Mutation That Signals Aggressive Melanoma

Newswise — New York, NY (April 6, 2022)— Mutation of a gene called ARID2 plays a role in increasing the chance that melanoma, a deadly skin cancer, will turn dangerously metastatic, Mount Sinai researchers report. The findings suggest that patients whose melanoma tumors have an ARID2 mutation may have a more aggressive cancer and may need to be treated … Continued

Read More

PRESS RELEASE: The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2022 Prize for Early-Career, Radically Innovative Cancer Researchers 

The Pershing Square Sohn Cancer Research Alliance Is Now Accepting Applications for its 2022 Prize for Early-Career, Radically Innovative Cancer Researchers  NEW YORK, OCTOBER 4, 2021 (Business Wire) – The Pershing Square Sohn Cancer Research Alliance (PSSCRA) today announced the opening of applications for the 2022 Pershing Square Sohn Prize for Young Investigators in Cancer … Continued

Read More